Systemic sclerosis: one year in review 2025. [Review]

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All Authors

Di Battista, M.
Lepri, G.
Codullo, V.
Bianchessi, L.
Ghezzi, G.
Della Rossa, A.
Guiducci, S.
Del Galdo, F.

LTHT Author

Del Galdo, Francesco

LTHT Department

NIHR Leeds Biomedical Research Centre
Rheumatology

Non Medic

Publication Date

2025

Item Type

Journal Article
Review

Language

Subject

Subject Headings

Abstract

Systemic sclerosis is a rare and chronic connective tissue disease with a complex pathogenesis and highly heterogeneous clinical manifestations. Although significant progress has been made in understanding its underlying mechanisms, early diagnosis and therapeutic strategies, SSc remains a clinical challenge. Each year, several studies explore new insights into its pathogenesis, organ involvement, and treatment. This review provides an overview of the most relevant studies published in the literature in 2024.

Journal

Clinical & Experimental Rheumatology