A National Audit of Current UK Practice on the Use of Anti-Emetics for Chemotherapy-Induced Nausea and Vomiting in Children.

Neumann, E.; Jackson, TJ.; Morgan, JE.; Phillips, R.; Bate, J.

A National Audit of Current UK Practice on the Use of Anti-Emetics for Chemotherapy-Induced Nausea and Vomiting in Children.

All Authors

Neumann, E.

Jackson, TJ.

Morgan, JE.

Phillips, R.

Bate, J.

LTHT Author

Morgan, Jessica

LTHT Department

Leeds Children's Hospital
Children & Teenage Oncology & Haematology

Publication Date

2025

Item Type

Journal Article

Abstract

This UK national audit aimed to assess adherence to evidence-based chemotherapy-induced nausea and vomiting (CINV) guidelines for children with cancer, which emphasise treatment emetogenicity assessment, symptom monitoring and appropriate antiemetic use. Data from 99 inpatient episodes in 12 centres were collected over 5 days in January 2024 via an anonymised survey. Concordance with 2018 CCLG guidelines was 83%, with 6% of cases overestimated and 11% underestimated levels of emetogenicity. This first UK national audit demonstrates generally good alignment with guidelines. Future audits should include prescribing practices in outpatient and ambulatory settings to provide a more comprehensive evaluation of CINV management.