Regression of cardiac angiosarcoma in a 17-year-old: a percutaneous biopsy effect.
No Thumbnail Available
All Authors
Sharrack, N.
Parent, M.
Lethaby, C.
Rosendahl, U.
Lyon, AR.
Farooq, M.
Jamil, H.
Greenwood, JP.
Plein, S.
Kidambi, A.
LTHT Author
Sharrack, Noor
Lethaby, Christopher
Kidambi, Ananth
Lethaby, Christopher
Kidambi, Ananth
LTHT Department
Children & Teenage Oncology & Haematology
Leeds Children's Hospital
Cardiology
Cardio-Respiratory
Leeds Children's Hospital
Cardiology
Cardio-Respiratory
Non Medic
Publication Date
2024
Item Type
Journal Article
Language
Subject
Subject Headings
Abstract
BACKGROUND: Cardiac angiosarcoma is a very rare and aggressive primary cardiac tumor associated with poor prognosis. Diagnosis is often delayed due to non-specific symptoms, with most cases involving metastases at the time of diagnosis. We describe a unique case of apparent tumor regression of cardiac angiosarcoma post percutaneous biopsy.
CASE PRESENTATION: A young male was admitted with suspected pericarditis. Echocardiogram revealed a pericardial mass. Cardiovascular magnetic resonance (CMR) suggested primary cardiac malignancy. Percutaneous biopsy was inconclusive, with subsequent CMR demonstrating apparent tumor regression. Interval imaging revealed further tumor growth, and surgical biopsy revealed primary cardiac angiosarcoma (PCAS). Causes of tumor regression following percutaneous biopsy are discussed.
CONCLUSIONS: Cases of suspected primary cardiac malignancy require careful follow up with serial multimodality imaging. Percutaneous biopsy effects should be considered in cases of tumor regression, and serial imaging should be planned afterwards.
Journal
Cardio-Oncology