Successful pregnancy after reconstructive surgery for a woman with complete cervical and vaginal agenesis - a case report and literature review. [Review]
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All Authors
Tamblyn, JA.
Salahuddin, S.
Morley, LC.
Balen, AH.
LTHT Author
Tamblyn, Jennifer
Salahuddin, Syed
Morley, Lara
Balen, Adam
Salahuddin, Syed
Morley, Lara
Balen, Adam
LTHT Department
Women's Services
Obstetrics & Gynaecology
Centre for Reproductive Medicine
Leeds Children's Hospital
Paediatric Surgery
Obstetrics & Gynaecology
Centre for Reproductive Medicine
Leeds Children's Hospital
Paediatric Surgery
Non Medic
Publication Date
2026
Item Type
Journal Article
Case Reports
Review
Case Reports
Review
Language
Subject
PAEDIATRICS , PREGNANCY
Subject Headings
Abstract
Congenital cervical agenesis is a rare but important obstructive cause of primary amenorrhoea. Initial diagnosis is often delayed. With advances in reconstructive surgery, fertility restoration is now a realistic option for some women. We present a case of complete cervical and vaginal agenesis diagnosed in a 16-year-old girl who presented with cyclical pelvic pain and primary amenorrhoea. Following successful vaginoplasty and direct uterovaginal anastomosis, regular, pain-free menses, and later, uncomplicated sexual intercourse was achieved. Following a 10-year period of primary infertility and unsuccessful assisted reproduction treatment, natural pregnancy was achieved with the birth of a healthy male infant by caesarean section at term. This report aims to highlight the potential complexities of both natural and assisted conception following corrective uterine surgery. The importance of an individualised, multi-disciplinary approach to care is also highlighted.
Journal
Human Fertility