HOW I DO IT: Cushing's disease-selective adenomectomy via an endoscopic transsphenoidal approach.
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All Authors
Phillips, N.
Nix, P.
De Santos, M.
LTHT Author
Phillips, Nick
Nix, Paul
De Santos, Mikhail
Nix, Paul
De Santos, Mikhail
LTHT Department
Neurosurgery
Head & Neck
Ear, Nose & Throat
Head & Neck
Ear, Nose & Throat
Non Medic
Publication Date
2024
Item Type
Journal Article
Case Reports
Case Reports
Language
Subject
Subject Headings
Abstract
BACKGROUND: An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing's Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.
METHOD: Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.
CONCLUSION: Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.
Journal
Acta Neurochirurgica