Neuropathological findings in essential tremor. [Review]

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All Authors

Mavroudis, I.
Petridis, F.

LTHT Author

Mavroudis, Ioannis

LTHT Department

Neurosciences

Non Medic

Publication Date

2025

Item Type

Journal Article
Review

Language

Subject

Subject Headings

Abstract

Essential tremor (ET) is one of the most common neurological conditions and the most common movement disorder. The pathophysiological mechanisms that underlie this entity have not yet been described. However, recent post-mortem brain studies have provided useful insight into the underlying pathology of ET. Two brain areas have been consistently found to present neuropathological alterations in patients with ET: the brainstem, for presence of Lewy bodies or neuronal depletion, and the cerebellum, regarding Purkinje cells' morphology and density. In the present study we aim to review the literature on the main neuropathological findings in ET brains.

Journal

Folia Neuropathologica

URI

https://hdl.handle.net/20.500.14838/229

DOI

https://dx.doi.org/10.5114/fn.2024.140569

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