Recent advances in the diagnosis and management of B3 lesions.
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All Authors
Shaaban, A.M.
McMahon, M.A.
Sharma, N.
LTHT Author
McMahon, Michelle
Sharma, Nisha
Sharma, Nisha
LTHT Department
Radiology
Breast Imaging
Breast Screening
Breast Imaging
Breast Screening
Non Medic
Publication Date
2025
Item Type
Review
Language
Subject
Subject Headings
Abstract
Lesions of uncertain malignant potential (B3 lesions) comprise a number of diagnostic entities; some of which are associated with atypia. These lesions can be challenging diagnostically and management wise. Traditionally, diagnostic surgical excision was performed for those lesions. More recently, vacuum assisted excision has been adopted for adequate sampling of those lesions. The last couple of years has witnessed advances in the understanding of the biology and outcome of B3 lesions with relevant guidelines produced to guide the multidisciplinary teams managing patients with B3 diagnoses. This review covers the histological and radiological features of B3 lesions, updates on the current evidence and new management guidelines and provides practical tips for pathologists involved in the diagnosis and multidisciplinary team discussion of those difficult lesions.
Journal
Diagnostic Histopathology