Outcomes of N0 Necks in Primary Parotid Carcinoma: A Multi-Institution Study Over Ten Years.
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All Authors
Cunniffe, H.
Wong, J.
Jackson, R.
Kornfeld, B.
Addison, A.
Karamali, K.
Fish, B.
Nassif, R.
LTHT Author
Jackson, Richard
LTHT Department
Head & Neck
Ear, Nose & Throat
Ear, Nose & Throat
Non Medic
Publication Date
2025
Item Type
Journal Article
Multicenter Study
Multicenter Study
Language
Subject
Subject Headings
Abstract
AIMS: To determine in patients with clinical and radiological N0 necks in primary parotid carcinoma: (1) Rate of occult node positivity post-neck dissection. (2) Outcomes following elective neck dissection +/- radiotherapy. (3) Factors predicting recurrence and mortality following treatment.
METHODS: A retrospective study on patients diagnosed with malignant neoplasm of the parotid between January 2007 and December 2018 from three UK tertiary centres.
RESULTS: One hundred and thirty-four patients were identified. 6% (4/62) of patients who underwent neck dissection for radiologically N0 neck had positive lymph nodes. There was no statistically significant feature associated with recurrence and disease-related mortality, but recurrence was associated with an increased risk of mortality (HR 1.444).
CONCLUSION: This study has demonstrated a low rate of occult nodal disease in N0 parotid malignancy and suggests that high-grade disease has a higher risk of nodal disease and recurrence. These patients may benefit from elective neck treatment, but more prospective data is required.
Journal
Clinical Otolaryngology