Efficacy, safety, and public attitude toward COVID-19 vaccines: A systematic review.
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All Authors
Josiah, BO.
Uzor, CC.
Duncan, BA.
Enebeli, EC.
Otoboyor, NL.
LTHT Author
Enebeli, Emmanuel Chukwunwike
LTHT Department
Adult Critical Care
Non Medic
Staff Nurse
Publication Date
2023
Item Type
Systematic Review
Journal Article
Journal Article
Language
Subject
Subject Headings
Abstract
Background: This paper reviews some of the literature on the safety and efficacy of different COVID-19 vaccines, the attitudes, and perceptions of people towards the vaccines, and the factor underlying such perceptions and behavior.
Methods: Two major databases (PubMed and Epistemonikos) were checked using search expansion mechanisms and several search strings. After the title, abstract, and full-text analysis, 19 studies were selected for review.
Results: The seven different vaccines studied all have supporting data on their efficacy in the reduction of COVID-19 cases, prevention of hospitalization after infection, and reduction in the mortality rate of COVID-19 patients. There was high hesitancy about the COVID-19 vaccine and the perceived efficacy and safety of the vaccines are less than recorded in clinical data. Distrust of the vaccines, their manufacturers and different institutions and governments, personal beliefs and feelings, age, gender, education, and socioeconomic status were identified factors affecting behaviors towards the COVID-19 vaccines.
Conclusion: Several articles support the efficacy of COVID-19 vaccines, but general awareness and conception about them vary, including hesitancy, distrust, and some acceptance. Many factors affected the perception and attitude of people toward these vaccines. More clinical data on the efficacy and safety of COVID-19 vaccines should be generated to help boost confidence among users.
Journal
Annals of African Medicine