A standardised approach to the pathological dissection and reporting of pelvic exenteration specimens: Recommendations from the UK Pelvic Exenteration Network (UKPEN).

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All Authors

Aldridge, J.
Young, C.
Tiernan, J.
Quyn, A.
Tolan, D.
Jenkins, JT.
Burns, E.
Martinez, A.
Bateman, AC.
Mirnezami, A.

LTHT Author

Aldridge, Jocelyn
Young, Caroline
Tiernan, Jim Patrick
Quyn, Aaron
Tolan, Damian
West, Nick

LTHT Department

Pathology
Histopathology
Abdominal Medicine & Surgery
Colorectal Surgery
John Goligher Colorectal Unit
Radiology

Non Medic

Publication Date

2026

Item Type

Journal Article

Language

Subject

RECTAL NEOPLASMS , PATHOLOGICAL CONDITIONS, SIGNS AND SYMPTOMS

Subject Headings

Abstract

AIM: Pelvic exenterations are complex operations associated with significant morbidity and resource implications. Resection is undertaken with curative intent, and achieving clear margins is paramount to successful oncological outcomes. Comprehensive pathological reporting is essential, yet there are no internationally agreed guidelines describing an optimal approach. METHODS: This article presents a standardised approach to the pathological dissection and reporting of pelvic exenteration specimens, endorsed by the UK Pelvic Exenteration Network (UKPEN). This includes all relevant steps of the clinical pathway, from acknowledging the importance of pathology involvement in pre-operative radiological planning to post-operative correlation meetings. Key recommendations are exemplified with illustrative examples. CONCLUSION: Standardisation of pelvic exenteration pathology will contribute to optimal patient care, enhance multidisciplinary learning and service development, provide quality assurance and auditable standards and facilitate national and international research.

Journal

Colorectal Disease