MS care: integrating advanced therapies and holistic management. [Review]
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All Authors
Giovannoni, G.
Ford, HL.
Schmierer, K.
Middleton, R.
Stennett, AM.
Pomeroy, I.
Fisniku, L.
Scalfari, A.
Bannon, C.
Stross, R.
LTHT Author
Ford, Helen
LTHT Department
Neurology
Non Medic
Publication Date
2023
Item Type
Journal Article
Review
Review
Language
Subject
Subject Headings
Abstract
Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a "brain-healthy" and "metabolically-healthy" lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. We emphasise the importance of self-management and adopting a multidisciplinary, collaborative and person-centred approach to care that encompasses the healthcare team, family members and community support groups.
Journal
Frontiers in neurology [electronic resource].