Hepatocellular carcinoma surveillance: minimum standards.
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All Authors
Sharma, R.
Aravinthan, A.D.
Qurashi, M.
Stenberg, B.
Marshall, A.
Hollywood, C.
Macdonald, D.
Foster, G.R.
Rowe, I.A.
Franklin, J.
LTHT Author
Jones, Rebecca
LTHT Department
Abdominal Medicine & Surgery
Liver Unit
Hepatology
Liver Unit
Hepatology
Non Medic
Publication Date
2025
Item Type
Review
Language
Subject
Subject Headings
Abstract
Hepatocellular carcinoma (HCC) is a rapidly growing cause of cancer-related deaths in the UK, with early detection being critical for improving survival rates. Despite clear guidelines recommending 6-monthly surveillance for at-risk populations, participation remains low, with an estimated 20% of eligible patients attending regular surveillance. This guidance outlines the minimum standards for delivering effective HCC surveillance, emphasising the need for integrated patient tracking, digital call-recall systems and a multifaceted approach to engagement. Combining ultrasound with serum alpha-fetoprotein (AFP) improves detection rates, though AFP alone is insufficient due to its variability. The recommendations aim to increase surveillance adherence, enhance early diagnosis and ultimately improve outcomes for patients at risk of HCC.
Journal
Frontline Gastroenterology